Polygonum multiflorum extract |He shou wu extract

He shou wu extract is one of those holy roots. and it has a whole lot of document use since ancient times, as well as revered by the modern scientific community. firstly,Polygonum multiflorum, is a popular herb in traditional Chinese medicine. secondly , Commonly known as He shou wu in China and Fo-ti in North America, further more ,studies have shown this herb to be beneficial in the treatment of cancer, supporting diabetes, hair loss, hardening of the arteries, and neurodegenerative diseases.

On the other hand ,Traditionally, its also revered as a spiritual herb, known amongst monks and healers to boost spiritual potency.

HEALING BENEFITS OF HE SHOU WU EXTRACT FOUND IN SCIENTIFIC STUDIES:
*written by Joe Cohen:

– Anti-inflammatory:

For example ,The TSG and emotion in HE SHOU WU EXTRACT has been studied for its decrease in inflammation. Emodin protects microglia cells in the brain from inflammation due to lipopolysaccharides through AMPK/Nrf2 activation [R].

– Promotes Immune Function:

I n the same vein, The sugars (rhamnose, arabinose, xylose, and glucose) and anthraquinone glycosides found within Fo-ti. which it can improve immune response .

and moreover  ,it can  overall immune system function (immunomodulatory effect).

In addition ,Fo-ti boosts the immune system by increasing the production of T and B cells. and it can improving the activities of the immune cells .as well as increasing the secretion of the inflammatory tumor necrosis factor. Further, Fo-ti increases the activity of natural killer (NK) cells [R, R].

– Anti-Viral:

Therefore ,Fo-ti exhibited anti-HIV by preventing the virus from entering lymphocytes in a cell-based study [R].

– Protects the Liver:

The anthraquinones and polysaccharides found in Fo-ti protect the liver  .which by reducing inflammation, preventing fat oxidation,.and moreover , increasing antioxidanteffects [R, R].

– Protects the bones from oxidative stress:

TSG from Fo-ti extract protects the bone-making cells (osteoblasts) from oxidative damage in a cell-based study. it  suggesting that TSG may protect against osteoporosis due to oxidative stress [R].

– Protects tissue oxygenation in Diabetes:

n short, 2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside protects against kidney damage  from high blood sugar in diabetic mice . which through SIRT1 and TGF-beta1 pathways [R, R].

– Neuroprotective effect:

Meanwhile ,Studies show that it may help with Alzheimers Disease.

Therefore ,tetrahydroxystilbene glucoside from Fo-ti helps with memory deficit [R]. A small Chinese clinical trial found that Fo-ti extract is effective against Alzheimer’s disease [R].

Tetrahydroxystilbene glucoside helps slow down age-related memory loss in rats [R].In a cell-based study, treatment with a Fo-ti root extract reduced amyloid plaque that can cause Alzheimer‘s disease [R].

Potential side effects:

Above all , The best-known toxicity of P. multiflorum is the induction of hepatotoxicity (liver damage) . when used in very high consistent doses.

for instance ,Several cases of hepatotoxicity due to P. multiflorum have been reported in patients from Australia, China, Italy, Japan, the Netherlands and Slovakia.  who were taking the product for hair loss, chronic prostatitis or to boost the immune system [R, R, R, R].

The main chemicals responsible for the hepatotoxicity of P. multiflorumare free anthraquinones such as emodin and physcion [R].